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Today's Stories June 4, 2007 Patrick Cockburn An Interview with Moqtada al-Sadr Diana Johnstone Sarko and the Ghosts of May, 1968 Susan Rosenthal, MD How Cindy Sheehan Unmasked the Democrats Richard Ward The Right of Return to New Orleans   June 2 / 3, 2007 Alexander Cockburn The Last of the Texas Outsiders Marc Levy Iraq Dead Ahead: a Brief Military History and Civilian Guide to Arlington National Cemetery Martin Smith Camilo Mejía's War: From Foot Soldier for Empire to Rebel for Peace Diana Johnstone Great Power Meddling in Kosovo John Ross The Oaxaca Volcano Stews Uri Avnery On Generals and Admirals Sunsara Taylor This is Not a Story About Cindy Sheehan Richard Neville Were the Hippies Right? P. Sainath The Farm Crisis and 100,000 Indian Widows Missy Comley Beattie Let's Roar Nisrine Abiad and Victor Kattan The Hariri Tribunal: a Fait Accompli? Rannie Amiri Lebanon, Bush and the Three Stooges Margot Pepper Deconstructing "Return to Sender" Eric Stewart Censorship and Cop Brutality in the New Bison Wars Ralph Nader The Halberstam Camp Dan Bacher A Victory for the Fish Shaun Harkin and Sandy Boyer Irish War Protesters on Trial Richard Rhames Selling Five Acres in Crawford Frederick Hudson The Rediscovery of Ella Fitzgerald Poets' Basement Lindorff, Landau and Buknatski Website of the Weekend Gimme Shelter June 1, 2007 Dave Marsh The FBI and the Godfather (of Soul): James Brown's FBI Files Saul Landau Return to Cuba: 47 Years Later in Havana David Phinney How the Baghdad Embassy Was Built: Forced Labor and Worker Abuse Robert Jensen The Bigot and the Boycott Stanley Heller Arrest Robert McNamara Yifat Susskind Indigenous Women Fight Back Robert Weissman Corporate Power Since 1980 Paul Buchheit Africa and Its Discontents William S. Lind The Folly of Maximalist Objectives Sherwood Ross 78,000 Iraqis Have Been Killed by Coalition Airstrikes Stephen Lendman Terrorism Defined Website of the Day Desert Autonomous Zone May 31, 2007 Robert Bryce The Language Barrier Patrick Cockburn Killing with Impunity: Iraq's Militias Under the Surge Gary Leupp Appropriate Disillusionment: the Despair of Cindy Sheehan and Andrew Bacevich Kathy Kelly Being Hope Marjorie Cohn The Unitary King George Chris Kutalik and Tiffany Ten Eyck Fallout from the Sale of Chrysler: Jobs, Health Care, Pensions, All in Jeopardy Corporate Crime Reporter Zheng Xiaoyu Meet Lester Crawford Dave Lindorff Our Monica: a Hero of the Constitution Website of the Day Know Your Rights!   May 30, 2007 James Ridgeway The Bi-Partisan Con on Synthetic Fuels Franklin Lamb Lebanon and the Planned US Airbase at Kaleiaat Terrence E. Paupp Withdrawal Symptoms Uri Avnery To the Shores of Tripoli Alan Maass and Jeffrey St. Clair The Green Masquerade: Corporate America's Latest Counter-Attack Rock and Rap Confidential Watching the Detectives: the Political Censorship of Hip Hop Ralph Nader Taming the Giant Corporation Nirmal Ghosh China, CITES and the Fate of the Tiger Jean Daniels Dealing Democrats: Folding to Mr. 28% Tom Barry Meet Robert Zoellick: Bush's Pick to Head World Bank Website of the Day Petuuche Gilbert on the Rights of Indigenous People May 29, 2007 Stephen Soldz Shrinks and the SERE Technique at Guantanamo Eliza Ernshire Refugees Forever: Inside Bedawi Camp Ron Jacobs The Exit of Cindy Sheehan Dave Lindorff Whatever Happened to Signing Statements? Evelyn Pringle What Qualifies Bush to Lead Iraq War Mike Whitney Bush's New Middle East David Swanson How We Got Here: The Democrats and the Antiwar Movement John Holt Gating Montana, Part Two: the Feedback Loop Cynthia McKinney Dreaming of a True Memorial Day Martha Rosenberg Mad Cows, Mad Pigs and the Horse Slaughter Lobby Website of the Day The Ruminant May 28, 2007 Bill Quigley Katrina Activists: "Less Meeting, More Fighting" Col. Dan Smith The Paranoid and the Dead Cindy Sheehan Why I Am Leaving the Democratic Party Dr. Susan Block Dr. Laura's Little Monster Jeeni Criscenzo What I Learned About Being a Dickhead Douglas Valentine Memorial Day: a Poem Website of the Day Peace TV     May 26 / 27, 2007 Alexander Cockburn The Greenhousers Strike Back and Out Michael Donnelly Green Sabotage as "Terrorism" Patrick Cockburn Sadr's Dramatic Reappearance Franklin Lamb Inside Nahr el-Bared: "Another Waco in the Making" Jean Bricmont The Moral Collapse of the Moral Left Gary Leupp Cheney, Israel and Iran James Petras Imperial Rot: The Beginning of the End of the American Empire? William Peace Ashley Unlawfully Sterilized Judith and John Sharpe The Saga of Our Son, Lt. Commander John Sharpe: Under Investigation for Antiwar Sentiments Saul Landau Four Dead in Ohio: From Kent State to Tiannamen Square Paul Craig Roberts Democracy in Iraq, Tyranny at Home? Jonathan M. Feldman Congress and the Iraq War Vote Dave Lindorff Democratic Blood Money Missy Beattie Congress Plays Dead Mike Whitney Swan Song of the Democrats Badruddin Khan AIPAC Intervenes on Iran and Congress Folds, Again Ron Jacobs The Crime of Silence Zoe Blunt The Antidote to Despair Arjun Chowdhury, Mark Hoffman and Kevin Parsneau The Can-Do Troops and the New Anti-Politics Heather Gray The 1969 Riots Against the Chinese in Malaysia: a New Explanation N. D. Jayaprakash Disarmament Negotiations: A History and Prospectus Joe Allen and Paul D'Amato Cartoons with Class Poets' Basement Gowani, Ford, Anderson and Simon Website of the Weekend Addicted to War May 25, 2007 Robert Jensen What the Finkelstein Tenure Fight Tells Us About the State of Academia David Vest So You Thought They'd End the War John Stauber Democratic Spin Won't End the War in Iraq Evelyn Pringle Congress Gives War Profiteers Another $100 Billion Corporate Crime Reporter Why Corporate Social Responsibility Programs are a Fraud Susan Rosenthal, MD What's Missing from the Health Care Debate Roberto Rodriguez Us vs. Them in the Immigration Debate Steve Fournier Goodie, Goodie Goodling Patrick McElwee Venezuela and RCTV: Is Free Speech Really at Stake? Robert Weissman Resisting the Commercialization of Public Schools Website of the Day New DNC Motto: "We Suck"     May 24, 2007 Franklin Lamb Who's Behind the Fighting in North Lebanon Corporate Crime Reporter House Democrats Buckle to Big Oil: Strip Down Price Gouging Bill Robert Fantina Giuliani: Righteous, Indignant and Wrong Norman Solomon Deadly Illusions, Rest in Peace Dave Lindorff Kerrycrats All!: Now It's a Democratic War Sen. Russell Feingold We are Moving Backwards on Iraq Fred Gardner Doctor of Last Resort Mike Whitney Paulson in China Kevin Parsneau, Arjun Chowdhury and Mark Hoffman Becoming Imperialist: a Warning to Iraq War Critics Caroline Paul My Brother the "Terrorist": Animal Liberation and Prosecutorial Overkill Eva Liddell In Defense of Lying on Job Applications Website of the Day Johnny's Jumped the Shark May 23, 2007 Patrick Cockburn Opium: Iraq's Newest Export Rev. William Alberts Faith-Based Imperialism Joe DeRaymond Colombia's Civil War and the US Sudhanva Deshpande and Vijay Prashad The Political Economy of a Crisis Paul Craig Roberts Republicans in Self-Destruct Mode Glen Ford A Less "White" USA Rannie Amiri The Great Bank Heist of Tripoli China Hand China's Great Wall of Cash? Zoe Blunt Tales from the Tree Tops: Veteran Tree Sitter Tells All Nivien Saleh Who's to Blame for Iraq? Website of the Day Debating the Israel Lobby May 22, 2007 Robert Fisk A Front Row Seat for the Bloodbath in Lebanon Joshua Frank Hillary Clinton's Achilles Heel? Harvey Wasserman Drop Dead, New Yorkers: Giuliani and the Toxic Fallout from 9/11 David Mos Masumoto An Orchard Without Workers Sonja Karkar Israeli Forest Named After Australian Prime Minister Conn Hallinan The Afghan Quagmire Dave Lindorff A Widening Chasm on Impeachment Jeffrey Kolakowski Meet Us in Detroit: an Open Letter to John Konyers Evelyn Pringle A Misleading Suicide Warning Jim Baumer Politics Gary, Indiana-Style Website of the Day Should the Democrats Fear Mike Gravel? May 21, 2007 Patrick Cockburn The Secret US Plot to Kill Sadr Nicole Colson Much Ado About the Fort Dix Pizza Plot John Ross Shooting for the Top: Mexico's Drug Gangs Take Aim at Calderon Stephen Fleischman Werewolf of Washington: Wolfowitz Comes Full Circle M. Shahid Alam Chosenness and Israeli Exceptionalism Ron Jacobs Green Mountain Days: Return to Vermont Peter Rost, MD Pfizer CFO Resigns Alan Farago Can the Everglades Save Florida? Paul Buchheit The Dark Side of Democracy Promotion Website of the Day Code Monkey: Live! May 19 / 20, 2007 Andrew Cockburn Why America Lost the War in Iraq Uri Avnery The Next War Peter Gelderloos My Arrest in Spain: The Easy Road from Tourism to Terrorism Saul Landau Bush's Accomplishments Robert Fantina Iraq's History: Lessons for the Present and the Future Fred Gardner Hemp vs. Pot, a False Dichotomy Ralph Nader Timid Democrats and the Antiwar Movement Jean Daniels Waiting for Obama Reza Fiyouzat Vietnam Syndrome: Dead or Alive? Missy Beattie Ron Paul, Rudy Giuliani and Osama's Fatwah Robert Alvarez Magical Thinking About Nuclear Waste Sonja Karkar The Palestinians of Iraq Dave Lindorff Mumia Case on Hold Jeff Sher Keep Workers Healthy and Reduce Health Care Cost: Eliminate Co-Pays Julian C. Holmes Torture, Maine Style Clancy Sigal Red Mutiny: 11 Fateful Days on the Battleship Potemkin Prairie Miller The Murder of Fred Hampton James Murren The Dog Ate Karl Rove's Homework: When Turd Blossom Met the Teachers of the Year Poets' Basement Davies, Valentine and Engel Website of the Weekend Yellowstone's Shame: Harassing Newborn Bison   May 18, 2007 Adam Jones When Does Genocide Purify? Ask the Pope Sharon Smith The Death of Triangulation Politics? Christopher Brauchli Cheney's Middle East Adventure Peter Rost, MD Bribes and Spies in the Drug Industry Denise Maloney Pictou The Murder of Our Mother, Anna Mae Pictou Aquash: After 31 Years, It is Time for Justice David Swanson Of Snoops and Dupes Ali Khan The Lawyers' Mutiny in Pakistan Susan Rosenthal, M.D. Cho Seung-Hui Delivers His Message Samer Assad Israel and the Refugees: Fifty-Nine Years of Dispossession CP News Service Bidding for Extinction: Ivory Trade on eBay Threatens Survival of Elephants Website of the Day Another War Criminal Goes to Harvard   May 17, 2007 Tariq Ali The General vs. the Judge Yifat Susskind Honor Killings in the New Iraq: The Murder of Du'a Aswad Dave Zirin Being Ali or Being Owned: an Open Letter to LeBron James Brian J. Foley Hell, No, Harry Won't Go! W. John Green The Godfather of Colombia: Uribe and the Para Scandal Eric Johnson-DeBaufre Challenges for the New Sanctuary Movement Badruddin Khan Rebirthing the Neocons: Bernard Lewis' Latest Call to Arms Martha Rosenberg From Cockfighting to Foie Gras: On the Menu and on the Docket China Hand Pope Rat in Brazil: "The Amazon Tribes Longed for Christianity!" Dan Vojir Falwell's Tinky Winky Legacy: Who Will Battle the Telebubby Threat Now? Website of the Day Welcome to the Terrordome May 16, 2007 Patrick Cockburn Chalabi Speaks Ashley Dawson Who's Afraid of Wolfowitz? Joshua Frank Obama's Cash Flow: Maverick or Kidder? Corporate Crime Reporter Corporate Drug Pushers Ray McGovern A Four-Letter Word for Tenet Glen Ford Black Labor and the Big Mission Joe Bageant The Ghosts of Timothy Leary and Hunter S. Thompson Sonja Karkar The 59-Year Catastrophe Mickey S. Huff Preaching Hate: Farewell, Falwell John Chuckman Falwell's Lone Act of Kindness Kaz Dziamka What Ever Happened to Rogerian Argument? Website of the Day We're All Going to Hell   May 15, 2007 Michael Neumann Two States, One State and Snake Oil Patrick Cockburn An American Nightmare Ashley Smith How the US Set Iraq on Fire Marc Gardner Parole and the Long-Distance Trucker Dave Lindorff and Linn Washington, Jr Mumia Case Reaches Its Climax Ben Terrall Benchmark as Theft: Iraq Oil Workers Strike to Stop Privatization Ron Jacobs Cheney Threatens More War Harvey Wasserman The Legacy of Seabrook Marcus Mabry Shopping During Katrina Dr. Susan Block Cheney and the DC Madam's Cookie Jar Website of the Day Save Jean Klock Park from the Mega-Developers!   May 14, 2007 Jennifer Roesch Giuliani Time: the Mussolini of Manhattan Jeffrey St. Clair Humans, CO2 and Climate Change George Bisharat For Palestinians, Memory Matters Diane Wachtell The Real Imus Lesson Ramzy Baroud From Palestine to Rotterdam Rosemary and Walter Brasch When the National Guard Goes Missing: An Ill Wind and American Policy Nafeez Mosaddeq Ahmed Blair's Exit Roberto Rodriguez The Elusive Bars of Justice Jonathan Culp Cutting Out Collage: Copyright and Art in Canada Website of the Day Uranium Rock May 12 / 13, 2007 Alexander Cockburn Who are the Merchants of Fear? Patrick Cockburn State of Surge Jeffrey St. Clair High Line Fever: a Trip Across the Dark Side of Montana Diane Farsetta Untold Stories from the Pat Tillman / Jessica Lynch Hearings Ralph Nader Strip Mining the Newsroom: Mr. Zell and the Tribune Company Jean Bricmont The Great Illusion: Sarkozy and the "Decline" of France Marcus Breen Cheering Sarkozy: the US Media and the Rightwing Takeover of France Joe Bageant Rising Above Politics Conn Hallinan European Missiles and the Camel's Nose Fred Gardner The Unreported I-880 Fire Juan Santos and Leslie Radford Public Terror: Escalating the War on Migrants Eve Bachrach Inside Colombia's Flower Industry Missy Comley Beattie Shame Ron Jacobs The Bitterness of Regis Debray Niranjan Ramakrishnan The Sepoy Mutiny After 150 Years Susie Day Jesus Christ Weds Pat Robertson Poets' Basement Newberry, Engel, Landau, Katz and Davies Website of the Weekend The Shipyard: Recycling as Art May 11, 2007 Patrick Cockburn Blair's Depature: the View from Baghdad Kathleen Christison Playing at Peace Mike Ferner Collateral Genocide John Holt Gating Montana: A Ghastly Disneyland with High Rise Outhouses Laurie Hasbrook This Minute and Then the Next: a Plea from an Antiwar Mother Christopher Brauchli The Children of Limbo: Will the Pope Finally Set Them Free? Margaret Kimberley GOP Openly Embraces Gipper Values: Racism, Violence and Control Dave Lindorff Use It or Lose It: The Democrats and the Impeachment Clause Nicole Colson Anger Erupts at Conditions in For-Profit Indiana Prison John V. Walsh Beware the Do-Gooders in Body Armor Website of the Day Take the Terrorist Quiz!   May 10, 2007 Tariq Ali Adieu, Blair, Adieu Patrick Cockburn Killing of Teachers Turns Iraqi Sunnis Against al--Qa'ida Neve Gordon and Yigal Bronner In Israel Not All Blood is the Same: The Death of Samir Dari Marjorie Cohn Fighting Terror Selectively: Washington and Posada Carriles David Rosen The New Disappeared: Sex Offenders, Civil Confinement and the Resurrection of "Evil" Alan Farago Why the Everglades Have Dried Up: Developers and the South Florida Drought John Hellman France: From Pétain to Sarkozy Kathy Rentenbach A 100 Days of Rafael Correa BANCO The Stage is Set for Sentencing Another Innocent Black Man Richard Rhames Is Paris Burning? Website of the Day Tame the Corporation May 9, 2007 Jeff Leys Iraq and Afghanistan Supplemental Spending, 2008 Patrick Cockburn An Interview with Iraq's Foreign Minister on Iran and Iraq Glen Ford No Black Plan for America's Cities Paula Rothenberg Feminism Then and Now Kathryn Weber A Conversation with Norman Finkelstein John Chuckman The Likely Historical Significance of the War in Iraq Jordan Flaherty Looking for Justice in Jena, Louisiana Dave Lindorff Pelosi's Toothless Threat to Sue Bush Stephen Lendman Criminalizing Speech: the War on Free Expression in a Post-9/11 World Website of the Day "Fifth and Market": a Short Film About the Iraq War     May 8, 2007 Dave Lindorff The Great Oil Robbery Patrick Cockburn The Horrific Stoning Death of a Yazidi Girl Sparks Waves of Revenge Killings Corporate Crime Reporter Snuff Politics: Democrats Escalate Attack on Single Payer Ralph Nader The People's Crusade of Mike Gravel Malini Johar Schueller Decoding Harlan Ullman: Shock and Awe as Sexual Fantasy Juan Santos The Hate Equation: Targeting Migrant Children in LA Dave Zirin Jason Whitlock, the Clarence Thomas of Sportswriters? Joshua Frank The Price of Fire in Latin America Evelyn Pringle Serotonin Syndrome Eamonn McCann Irish Peace Dividend for Discredited Premiers Website of the Day The Pagan Science Monitor     May 7, 2007 Patrick Cockburn The Great Wall of Baghdad Rises Monica Benderman Land of Opportunity Greg Moses Hutto Prison Rebuffs UN Rapporteur Rannie Amiri The Sham at Sheikh: Iraq Regional Conference a Flop Fitrakis / Wasserman Media Silence on Kent State Revelations Fred Wilhelms Another Royalty Forfeiture From SoundExchange: And This Time It's Secret! Ramzy Baroud The Hourglass of Blood: Darfur Revisited Bruce K. Gagnon The Democrats Don't Own the Antiwar Movement T. W. Croft Home Movies from a Weekend in Paris--And Related Dreamscapes Sonja Karkar Prizes for Supporting Israel? Website of the Day Posada Carriles: the Declassified Record May 5 / 6, 2007 Alexander Cockburn Trying to Catch Up with the Voters William Blum How America Has Changed Iraq Uri Avnery Exercise in Escapism Franklin Lamb Harvard's Twisted Report on Israel's Invasion of Lebanon Fred Gardner Elective Surgeries Kill Lawrence R. Velvel The American Moral Meltdown Accelerates Missy Beattie Lying and Dying: The Moral Sensibility of Military Recruiters Robert Fantina Bush's Veto: Hypocritical Words and Actions Carla Blank American Massacres and the Media Linn Washington, Jr. The Long Ordeal of Harold Wilson Stephen F. Jackson Taking It to Drummond: Paramilitaries and Mining Companies in Colombia P. Sainath The Jailing of Indian Farmers Anthony Papa Time to End New York's War on Itself James T. Phillips Blather Cancer John Ross Last Days of the Willie Loman of the EZLN Stephen Lendman Chavez's Oil Policy Sparks Panic at Wall Street Journal Ben Terrall Iggy Pop at 60 CounterPunch Newswire Advice from a Geezer Assassin Poets' Basement Valentine, Engel and Davies Website of the Weekend Mountain Justice Summer   May 4, 2007 Patrick Cockburn How the Surge is Failing Col. Dan Smith From Watergate to Gonzogate Norman Solomon FOX on Wall Street Azmi Bishara Why is Israel After Me? Ron Jacobs Sitting in on Senator Kohl and the War Dave Lindorff Clinton and Byrd are Calling for Revocation of the Wrong AUMF Kevin Zeese The Democrats Cave to Bush Bob Fitrakis Why Four Died in Ohio: Kent State, Gov. Rhodes and the FBI Janet Kauffman "Stop the Mudness!" Bare Earth is Scorched Earth Website of the Day Let Us Gather in Missouri!   May 3, 2007 Jeff Halper The Livni-Rice Plan for the Middle East: a Just Peace or Apartheid? Christopher Brauchli Bush's Best and Brightest: From Dr. Keroack to Bernard Kerik Dave Zirin Talking Sports from Death Row: an Interview with Kevin Cooper Corporate Crime Reporter Big Pharma Gets Its Hooks into Seton Hall Law School Robert Fisk Olmert Comes Undone Mike Ferner Bush Veto, Right for the Wrong Reasons? Mike Whitney A Stock Market Post-Mortem Pham Binh The Democrats and War Funding Dave Lindorff Kucinich's Impeachment Train: Look Who Just Stepped Aboard Michael A. Johnson Tenet on 60 Minutes Website of the Day Olivia Wilde: the Interview   May 2, 2007 Saul Landau Would Jesus Wear a Rolex on His TV Show? Dr. Susan Block Hookergate II: Madame Julia's Big Black Book of Cheesy Republican Sex Acts Carla Blank Historical Amnesia: Worst U.S. Massacre? Margaret Kimberly The Candor of Mike Gravel: "These People Frighten Me" Kevin Zeese Durbin Gives Edwards More to Apologize For Carlos Villareal How "Law and Order" Covers for Bigotry in the Immigration Debate Michael Dickinson Trouble in Turkey: Criminalizing Political Art Tim Shorrock A Raw Deal Between Washington and Seoul: Corporate Interventionism as Trade Policy Alevtina Rea The Myth-Makers of Estonia William S. Lind General Incompetence: Col. Yingling and the Military Brass Website of the Day Good News: Rost's "ZubeGate Exposé Prompts Congressional Inquiry May 1, 2007 Andrew Cockburn How Rumsfeld Micromanaged Torture Fred Gardner Affirmative Abstinence: Adios, Randall Tobias, the Man Who Turned His Wife's Suicide into a Sales Pitch for Prozac Chase Madar Are Working Class Jobs Bad for Your Health? Ralph Nader Cheney and the BYU 25: Faith, Accountability and Protest in Utah John V. Walsh Edgy Dems Snarl at Their Antiwar Base Joshua Frank Obama, Incorporated Leslie Radford The Migrant Trap and the Migrant's Way Out Shaun Harkin An Interview with Nativo López on Immigration Bills and Protests Dave Lindorff Murtha Talks Impeachment Peter Rost, MD Inspector General Requests Meeting with Pfizer Whistleblower Peter Linebaugh May Day and Magna Carta Website of the Day Impeachment? Why Bother?         Subscribe Online

June 4, 2007 Partners in Crime The FDA, GlaxoSmithKline and the Avandia Disaster By EVELYN PRINGLE On May 21, 2007, the New England Journal of Medicine reported a study that found GlaxoSmithKline's diabetes drug Avandia is associated with a 43% increase in heart attacks and possibly a 64% increase in cardiovascular death. The NEJM said it posted the article online ahead of its June 6, 2007 print edition because of its medical importance. Experts point out that the studies analyzed for the NEJM report were not designed to look for heart risks, many were only 24 weeks long, and it may be that higher risks will appear after a longer term of use. Dr David Nathan, chief of diabetes care at Massachusetts General Hospital, who reviewed the paper for the NEJM, told the Associated Press, "This analysis is just scratching the surface of what may be there." Avandia (rosiglitazone) was FDA approved in 1999 for the treatment of type 2 diabetes, a disease that affects between 18 to 20 million Americans. When approved, Glaxo promoted Avandia as being safer than Rezulin, a diabetes drug removed from the market in 2000 after serious cases of liver damage developed in patients taking the drug. Avandia is currently the top selling diabetes drug with total US sales of $2.2 billion in 2006, according to IMS Health, a healthcare tracking information firm. A one-month supply sells for between $90 and $170, the Associated Press reported on May 23, 2007. "More than 6 million people worldwide," the Associated Press reports, "have taken the drug to control blood sugar since it came on the market eight years ago, and about 1 million Americans use it now." The FDA is going to have an extremely tough time wiggling out from under the rug of blame for this regulatory failure. The situation "reflects very badly on the FDA and on Glaxo," Dr Nathan said. "It's the FDA's responsibility to be monitoring this stuff." In an editorial that accompanied the study in the NEJM, Dr Bruce Psaty of the University of Washington and Dr Furberg of Wake Forest University wrote: The drug "represents a major failure of the drug-use and drug-approval processes in the United States." They also state that "the rationale for prescribing rosiglitazone at this time is unclear," because when the drug was approved its benefits were "at best mixed." Documents dating back 7 years show the FDA knew about the risks associated with Avandia and did nothing to protect consumers. The day after the new study appeared online, on May 23, 2007, Dr Sidney Wolfe, director of Public Citizen, a non-profit health research group, sent a letter to FDA Commissioner Andrew von Eschenbach, which described a July 16, 2002 FDA memo that showed FDA scientists had recommended that the label for Avandia be amended to include post-marketing reports of heart failure among patients taking the drug. "The failure of the FDA to act on the recommendations made almost five years ago by its Division of Drug Risk Evaluation is yet another case in which the conclusions of scientists who are engaged in post-market drug safety review are not taken seriously enough or addressed soon enough," Dr Wolfe said in a press release. "As a result," he stated further, "millions of people -- to the detriment of their health -- are prescribed drugs whose risks are dangerously understated, instead of being prescribed safer, equally or more effective alternative drugs." According to the memo, in July 2002, the FDA had 25 adverse reaction reports in which the use of Avandia resulted in hospitalization for heart failure. By the fall of 2006, the number of cases had increased to 415, Public Citizen reports. Another memo dated May 22, 2002, submitted to the FDA by Dr. Wolfe and Larry Sasich for an FDA Hearing on Risk Management of Prescription Drugs informed the panel that a Glaxo-employed physician had contacted Public Citizen to report that the company was concealing reports of serious problems found with the drug. "This week," they informed the FDA, "we received an anonymous call from a GlaxoSmithKline physician who was alarmed at the failure of his company to require a black box warning concerning heart failure caused by Avandia." "He maintained that the company currently has 450 reports of heart failure associated with the use of the drug and over 1200 reports of edema," the statement said. Nearly two years earlier, on March 15, 2000, Dr. John Buse, an Associate Professor of Medicine and Director of a Diabetes Care Center in Durham, North Carolina, sent a letter to then FDA Commissioner, Dr Jane Henney, warning the FDA about the risks of Avandia and describing the abuse of clinical trial data by Glaxo. "I remain concerned about the safety of rosiglitazone," Dr Buse wrote, "in light of its consistent negative impact on lipids documented in the FDA registration data as well as a worrisome trend in cardiovascular deaths and severe adverse events in the subjects exposed to rosiglitazone versus active comparators." Dr Buse warned, "I think the FDA has to act forcefully to prevent the rampant abuse of clinical trial data by SmithKline Beecham." He warned Dr Henney that Glaxo was overstating the safety of Avandia with respect to cardiovascular issues. "I have been shown glossy materials claiming that rosiglitazone has been uniquely studied in patients with preexisting cardiac disease," he wrote, "including patients with a number of associated conditions (such as unstable angina)." "I know for a fact," he noted, "that such patients are excluded in clinical trials as I am a PI [Principal Investigator] in one of their trials." Lawmakers in both Houses of Congress reacted to the news of another FDA regulatory failure immediately. On May 21, 2007 the US House of Representatives Committee on Oversight and Government Reform announced that a hearing would be held on June 6, 2007, at 10:00 am in Room 2154, Rayburn House Office Building, to assess the FDA's role in the evaluation of the safety of Avandia. Committee chairman, Rep Henry Waxman (D-CA) extended an invitation to the author of the NEJM article, cardiologist, Dr Steven Nissen of the Cleveland Clinic, to testify at the hearing and discuss his article. Dr Nissen and statistician Kathy Wolski, MPH, evaluated 42 studies involving nearly 28,000 patients and compared the 15,560 patients who were using Avandia to the patients who were not using the drug. The study found there were 86 myocardial infarctions in the Avandia group and 72 in the control group and there were 39 deaths from cardiovascular causes in Avandia patients compared to 22 in the control group. Rep Waxman also sent a letter to FDA Commissioner Andrew von Eschenbach requesting his testimony at the hearing. In addition, he instructed the Commissioner to provide the Committee with specific information from August 1, 2005, to the present to include: (1) A chronology of actions taken by FDA in relation to the cardiovascular safety of rosiglitazone; (2) All communications between GlaxoSmithKline and the FDA relating to cardiovascular safety of rosiglitazone; and (3) All internal FDA analyses, slide presentations, and memoranda relating to the cardiovascular safety of rosiglitazone. "In complying with this request," Rep Waxman advised the Commissioner, "you should produce all responsive documents in your possession, custody, or control." Rep Waxman also told the Commissioner, "you should submit a written certification, signed by you or your counsel, stating that: (1) a diligent search has been completed of all documents in your possession, custody, or control which reasonably could contain responsive documents: and (2) all documents located during the search that are responsive have been produced to the Committee or identified in a privilege log." And last but not least, Rep Waxman sent a letter to Glaxo CEO, Dr Jean-Pierre Garnier, asking him to appear. "We request that you come prepared to discuss your company's actions with regard to the cardiovascular safety of Avandia," the letter states. Over in the US Senate, Senators Max Baucus and Chuck Grassley, Chairman and Ranking Member of the Senate Committee on Finance, which has jurisdiction over the Medicare and Medicaid programs, issued a public statement and sent letters to the FDA and Glaxo demanding they provide specific documents and other information to the Committee. "What we are learning about the handling of Avandia," Sen Baucus said in the statement, "by both GlaxoSmithKline and the FDA is appalling and unacceptable." "Both the drug company and the FDA," he said, "have some major explaining to do about what they knew about Avandia, when they knew it, and why they didn't take immediate action to protect patients." "We need to know if this is another Vioxx," Senator Grassley stated, "where the FDA sat on its hands and endangered lives." "The FDA," he continued, "has talked a good game about how it's beefed up post-market surveillance over the last two years, but a case like this undermines that claim." Experts say the new study findings are alarming because two-thirds of the people with type 2 diabetes die of heart problems. In a May 21, 2007 letter to Christopher Viehbacher, President, US Pharmaceuticals, GlaxoSmithKline, Senators Baucus and Grassley wrote, "It is troubling, to say the least, that by taking Avandia, diabetics may be increasing their risk of the very adverse event that they hope to prevent by controlling their blood sugar." "To make matters worse," they advised, "American taxpayers have spent hundreds of millions of dollars on this drug through the Medicare and Medicaid programs." "One of the most immediate concerns to us," they told Mr Viehbacher, "are reports that GSK employees silenced one or more medical professionals who attempted to speak out about the potential for cardiovascular problems with Avandia." "This allegation is very serious and warrants further investigation," the Senators wrote. According to plaintiffs attorney, Karen Barth Menzies of Baum Hedlund, a law firm that has been litigating drug related cases against Glaxo since 2001, "The relationship between FDA and the drug industry is disturbing. We've seen internal correspondence between GSK and the FDA that would cause anyone to question the objectivity and regulatory effectiveness of the FDA. Apparently the FDA has failed yet again to protect the public - to the benefit of pharmaceutical industry profits. This failure, and FDA's derogatory attitude towards Dr. Nissen's study, should sound an alarm to all healthcare providers, patients and legislators that the problem is systemic. Patient safety commands serious change in the agency and the industry." Already, legal conferences are being scheduled to discuss the legal implications of this latest drug safety scandal. Karen Barth Menzies is an invited speaker at an upcoming legal conference regarding Avandia. The conference will include Avandia's background, the science behind the drug, its side effects as well as the FDA's role in regulating Avandia. Persons seeking legal advice regarding Avandia can contact Baum, Hedlund, Aristei, Goldman & Menzies at: (800) 827-0087; http://www.avandia-heart-lawyers.com/ Evelyn Pringle can be reached at: evelyn-pringle@sbcglobal.net

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